Lacher and Anderson discussed this phase diagram from the viewpoint of statistical thermodynamics based on the Fowler-Guggenheim treatment. They discovered that subcutaneous injection of the sodium salt of arsenous acid can cause the rapid disappearance of the parasite trypanosomes from the blood of mice and rats, but the parasites reappeared within a few days to cause the death of the animals. ![]() In 1902, Laveran and Mesnil of the Pasteur Institute found a method to infect mice with trypanosomes, and studied the effects of Fowler s Solution on them. He was made director of a new government laboratory in 1899 in Frankfurt, where he began to experiment in the synthesis of new substances not necessarily found in nature that could kill parasites or inhibit their growth without damaging the mammal. Now Hiickel extended the method to polyatomic molecules.67. 66 Hiickel s was part of a series of applications of the method of linear combination of atom wave functions ( atomic orbitals), a method that Felix Bloch had extended from H2+ to metals in 1928 and that Fowler s student, Lennard-Jones, had further developed for diatomic molecules in 1929. It was regarded by many people as the simplest of the quantum mechanical valence-bond methods based on the Schrodinger equation. ![]() Hiickel s application of this approach to the aromatic compounds gave new confidence to those physicists and chemists following up on the Hund- Mulliken analysis. The anatomical dead space can be measured by Fowler s method.
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